Association between neuropsychiatric morbidity and streptococcal infections in children.
نویسندگان
چکیده
We conducted a case control study to study the association between neuropsychiatric morbidity and group A streptococcal infections in children. Twenty two cases of neuropsychiatric morbidity were compared with 64 controls. Fourteen (63.6%) of the 22 cases were positive for ASO and/or ADNB while 21 of the 64 controls (32.8%) were positive for either or both antibodies (OR = 3.428; CI: 1.15-10.18; P=0.026). We conclude that there is a statistically significant association between neuropsychiatric morbidity and streptococcal infection in children.
منابع مشابه
Antibiotic prophylaxis with azithromycin or penicillin for childhood-onset neuropsychiatric disorders.
BACKGROUND The acronym PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) describes a subgroup of children with obsessive-compulsive disorder and/or tic disorder that experience symptom exacerbations following streptococcal infections. We hypothesized that the prevention of streptococcal infections among children in the PANDAS subgroup would decrea...
متن کاملReviews Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS): An Evolving Concept
Pediatric autoimmune neuropsychiatric disorders associated with streptococcus infections (PANDAS) originated from the observational work of Swedo and collaborators, who formalized their definition in 1998 in a set of operational criteria. The application of these criteria, which focuses on tics and obsessivecompulsive symptoms as core symptoms, has encountered difficulties, eventually leading t...
متن کاملPediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS): An Evolving Concept
Pediatric autoimmune neuropsychiatric disorders associated with streptococcus infections (PANDAS) originated from the observational work of Swedo and collaborators, who formalized their definition in 1998 in a set of operational criteria. The application of these criteria, which focuses on tics and obsessive-compulsive symptoms as core symptoms, has encountered difficulties, eventually leading ...
متن کاملP103: The Association between Antibasal Ganglia Antibodies of Streptococcal Infection and Neurological Conditions
The outbreak of the post-streptococcal neurological disorders related to the antibasal ganglia antibodies is broadening. In addition to the disorders such as chorea and obsessive-compulsive disorder which have been recognized previously, the movement and behavioral abnormalities are the other aspects of post-streptococcal neurological disorders. Streptococcus is a positive-gram and coccus...
متن کاملClinical factors associated with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections.
OBJECTIVE To explore associated clinical factors in children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS). STUDY DESIGN Children with tics, obsessive-compulsive disorder, or both (n=109) were examined with personal and family history, diagnostic interview, physical examination, medical record review, and measurement of baseline levels ...
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ورودعنوان ژورنال:
- Indian pediatrics
دوره 47 2 شماره
صفحات -
تاریخ انتشار 2010